Endocrine Abstracts

Purpose: GH deficiency (GHD) is associated with increased cardiovascular events, however, the detailed mechanisms have not been assessed yet extensively. We set up this study in order to evaluate cardiac, arterial, and endothelial function, by conventional echo, TDI, and biomarkers (proBNP and troponin I), in GHD patients by comparison with normal individuals with similar cardiovascular risk factors profile.Methods: Thirty GHD patients (46±14 years,...

ObjectiveDoes subclinical hypothyroidism (SCH)cause increased cardiovascular risk and how does treatment affect cardiac and vascular function in patients with SCH?MethodsCardiac function and central arterial stiffness(CAS)were measured in 20 females (mean age 50.1 plus/minus 4.1 years)with SCH (mean free T4 12.2 plus/minus 0.2 picomol per litre [normal range 9.8-22.1],median TSH 8.8 milliunits per litre[norma...